“Big Opportunity” behind scientific breakthrough and technological innovation would usually be underestimated or even be ignored at the early stage. However, we would be astonished by the tremendous transformations brought about by these technological progress only after years passed. Entrepreneurs in tech sector are the few people who had discovered and participated in these “opportunities” before others even noticed. As an angel investor, I was often amazed by those entrepreneurs with in-depth insight and thinking who touched on something nobody else understood. It was always a pleased and inspiring experience to talk with them! They shared their vision and strategy with great confidence and determination that you would join their adventures without any hesitation despite of risks and setbacks ahead.